Natural hazards can trigger disasters that lead to the collapse and reorganization of social-ecological systems. This reorganization can involve systems transitioning to more positive trajectories. The Panarchy framework, which conceptualizes social-ecological systems as dynamic interrelated adaptive cycles, is a common conceptual framework for understanding system reorganization. However, it is unclear how inequalities, social mechanisms known to influence disaster recovery outcomes, shape a system’s adaptive cycle post-disaster. Understanding the roles of inequalities can help develop social-ecological models to identify processes that build resilience into disaster recovery. We applied the Panarchy framework to inform propositions describing how inequalities can influence the reorganization of social-ecological systems after disasters triggered by natural hazards. We qualitatively analyzed a selection of case studies that discussed inequalities pre- and post-disasters and related these to adaptive-cycle system characteristics (i.e., potential, connectedness, and resilience). We identified three propositions: 1) The ability of groups to reorganize after a disaster varies across the inequality spectrum; 2) The reorganizing abilities of groups across the inequality spectrum impact one another; and 3) The presence of inequalities affect connectedness within the system. Incorporating these propositions into social-ecological system modeling can improve our understanding of how inequalities impact system reorganization. This information can support disaster recovery plans that strengthen a system’s ability to enter a more positive trajectory post-disaster.